Listeria monocytogenes represents one of the main risks for food safety worldwide.Two enzyme-based antimicrobials (enzybiotics) have been combined in a novel treatment against this pathogenic bacterium, resulting in a powerful synergistic Slippers effect.One of the enzymes is an endolysin from Listeria phage vB_LmoS_188 with amidase activity (hence

Over 1.2 million people in the United States are infected with the human immunodeficiency virus (HIV).Tremendous progress has been made over the past three decades on many fronts in the prevention and treatment of HIV-1 disease.However, HIV-1 infection is incurable and antiretroviral drugs continue to remain the only effective treatment option for

Abstract Background A continued effort in neuroscience aims to understand the way brain circuits consisting of diverse neuronal types generate complex behavior following sensory input.A common feature of vertebrate visual systems is that lower-order and higher-order visual areas are reciprocally connected.Feedforward projections confer visual respo

ABSTRACT Whole-genome sequencing has created a revolution in tuberculosis management by providing a comprehensive picture of the various genetic polymorphisms with unprecedented accuracy.Studies mapping genomic heterogeneity in clinical isolates of Mycobacterium tuberculosis using a whole-genome sequencing approach from high tuberculosis burden cou

Specific chromatin immunoprecipitation of salt-fractionated infected cell extracts has demonstrated that the CCCTC-binding factor (CTCF), a highly conserved, 11-zinc-finger DNA-binding protein with known roles in cellular and viral genome organization and gene expression, specifically binds the genome of Minute Mini Funnel Virus of Mice (MVM).Mutat